START WITH ANORO TO MAXIMIZE BRONCHODILATION2*

The 2 components of ANORO, LAMA & LABA, work together to increase bronchodilation2

Constricted airway representation
Constricted airway representation
LABA opens constricted airways
LAMA keeps the airways open
Airflow through lungs

LABA (vilanterol):

Activates β2 receptors and promotes bronchodilation.

LAMA (umeclidinium):

Inhibits binding of ACh to M3 muscarinic receptors; blocks the bronchoconstrictor effects of acetylcholine, leading to bronchodilation.

The 2 components, LAMA and LABA, could help maximize bronchodilation.* COPD symptoms look different for everyone, so consider if a LAMA/LABA is right for your patients.

*Defined as statistically significant improvements in lung function relative to its individual components and placebo in a 24-week, randomized, double-blind study in patients with COPD (N=1532). 8

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