START WITH ANORO TO MAXIMIZE BRONCHODILATION2*

The 2 components of ANORO, LAMA & LABA, work together to increase bronchodilation2

Hear From an Expert About the MOA of ANORO

Constricted airway representation
Constricted airway representation
LABA opens constricted airways
LAMA keeps the airways open
Airflow through lungs

LABA (vilanterol):

Activates β2 receptors and promotes bronchodilation.

LAMA (umeclidinium):

Inhibits binding of ACh to M3 muscarinic receptors; blocks the bronchoconstrictor effects of acetylcholine, leading to bronchodilation.

The 2 components, LAMA and LABA, could help maximize bronchodilation.* COPD symptoms look different for everyone, so consider if a LAMA/LABA is right for your patients.

*Defined as statistically significant improvements in lung function relative to its individual components and placebo in a 24-week, randomized, double-blind study in patients with COPD (N=1532). 8

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